Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
KIRC | rs4845780 | chr1:152488846 | T/G | 5.34E-5 | 517 | 34.38 | 44.97 | 37.9 | KM Plot |
KIRC | rs4862527 | chr4:186351447 | C/T | 1.23E-6 | 512 | 3.53 | 39.5 | 39.17 | KM Plot |
KIRC | rs4959176 | chr6:2374910 | A/C | 6.21E-7 | 521 | 40 | 39.07 | 15.55 | KM Plot |
KIRC | rs4959177 | chr6:2375660 | G/A | 6.73E-8 | 508 | 40 | 39.17 | 15.55 | KM Plot |
KIRC | rs4959180 | chr6:2387890 | T/C | 3.51E-6 | 508 | 41.73 | 38.35 | 15.55 | KM Plot |
KIRC | rs4959181 | chr6:2394789 | C/T | 1.53E-5 | 510 | 39.62 | 41.27 | 16.83 | KM Plot |
KIRC | rs4959182 | chr6:2394797 | C/T | 3.14E-7 | 512 | 41.27 | 39.17 | 12.45 | KM Plot |
KIRC | rs4959654 | chr6:2391525 | G/A | 2.39E-6 | 521 | 39.7 | 39.88 | 15.55 | KM Plot |
KIRC | rs4959665 | chr6:2423947 | G/A | 6.24E-6 | 512 | 39.62 | 40.6 | 19.03 | KM Plot |
KIRC | rs4959669 | chr6:2453470 | T/C | 6.64E-5 | 520 | 40.3 | 39.07 | 15.55 | KM Plot |
KIRC | rs500450 | chr11:125518345 | C/T | 0 | 519 | 1.37 | 41.73 | 39.2 | KM Plot |
KIRC | rs511822 | chr11:125534115 | C/T | 3.72E-14 | 521 | 1.4 | 38.1 | 39.62 | KM Plot |
KIRC | rs548252 | chr1:152489742 | A/G | 2.58E-5 | 527 | 37.9 | 43.57 | 34.83 | KM Plot |
KIRC | rs55648125 | chr6:50816718 | A/G | 2.38E-5 | 515 | 39.35 | 45.17 | 6.73 | KM Plot |
KIRC | rs55653665 | chr6:50812984 | T/C | 4.42E-6 | 520 | 41 | 40.3 | 15.3 | KM Plot |